Is the “Comb Over” Dying? A Mouse Model for Male Pattern Baldness (Androgenic Alopecia)

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Genetic basis of male pattern baldness.

Common pattern baldness (androgenetic alopecia) is the most common form of hair loss in humans. In Caucasians, normal male hair loss, commonly known as ‘‘male pattern baldness’’ (MPB; MIM 109200), is noticeable in about 20% of men aged 20, and increases steadily with age, so that a male in his 90s has a 90% chance of having some degree of MPB. In addition to being among the most common natural ...

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Surgical treatment of male pattern baldness.

1 Chandler JR. Malignant otitis externa. Laryngoscope 1968;78:1257-94. 2 Chandler JR. Pathogenesis and treatment of facial paralysis due to malignant otitis externa. Ann OtolRhinol Laryngol 1972;81:648-58. 3 SchwartzGA, BlumenkrantzMJ, StudmakerWHL. Neurologiccomplicationsofmalignantotitis extema. Neuroloz 1971;21:1077-84. 4 Joachims HZ. Malignant external otitis in children. Arch Otola,yngol 1...

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Evaluation of DNA Variants Associated with Androgenetic Alopecia and Their Potential to Predict Male Pattern Baldness

Androgenetic alopecia, known in men as male pattern baldness (MPB), is a very conspicuous condition that is particularly frequent among European men and thus contributes markedly to variation in physical appearance traits amongst Europeans. Recent studies have revealed multiple genes and polymorphisms to be associated with susceptibility to MPB. In this study, 50 candidate SNPs for androgenetic...

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Genetic prediction of male pattern baldness

Male pattern baldness can have substantial psychosocial effects, and it has been phenotypically linked to adverse health outcomes such as prostate cancer and cardiovascular disease. We explored the genetic architecture of the trait using data from over 52,000 male participants of UK Biobank, aged 40-69 years. We identified over 250 independent genetic loci associated with severe hair loss (P<5x...

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Male baldness.

BACKGROUND Male baldness is very common. Its effect on individuals is extremely variable, and in some people it will have a significant adverse effect on their quality of life. OBJECTIVE The objectives of this article are to help general practitioners (GPs) be aware of potential health problems related to male baldness, to have an approach to assessing hair loss and to be aware of treatment o...

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ژورنال

عنوان ژورنال: Endocrinology

سال: 2010

ISSN: 0013-7227,1945-7170

DOI: 10.1210/en.2010-0217